According to Barielle's webpage:
For Rough, Dry, Chapped Hands
An intensive overnight, moisture treatment that heals rough, dry, scaled, and chapped hands. This greaseless penetrating cream, formulated with revolutionary Oat Beta Glucan, provides a protective barrier directly on the skin to prevent dryness. Oat Beta Glucan is a unique ingredient derived from natural oats that acts as a natural anti-irritant which is safe for even the most sensitive skin.
Use: Massage cream into hands twice a day, once in the morning after bathing and once again in the evening before bed.
For Best results: Allow cream to penetrate overnight.
Ingredients: AQUA, ISOPROPYL PALMITATE, CETYL ALCOHOL, PEG-100 STEARATE, GLYCERYL STEARATE, CYCLOMETHICONE, PROPYLENE GLYCOL, SORBITOL, SOLUBLE MELANIN, OAT BETA GLUCAN, ROSEHIPS AND FRUCTOSE, CITRIC ACID, LACTIC ACID, TARTARIC ACID, PAPAYA (CARICA PAPAPYA) EXTRACT, APPLE PECTIN (PYRUS MALUS) AND LIPOSOMES, TOCOPHERYL ACETATE, ALOE BARBADENSIS GEL, HONEYSUCKLE (LONICERA CAPRIFOLIUM) AND JASMIN (JASMINUM OFFICINALE), PASSION FLOWER (PASSIFLORA CAMATA), GARDENIA (GARDENIA TAITENSIS), RED CLOVER (TRIFOLIUM PRATENSE), ECHINACEA (ECHINACEA ANGUSTIFOLIA), CHAPARRAL (LARREA MEXICANA), MILK THISTLE (SILYBUM MARIANUM) AND BLACK CURRANT (RIBES NIGRUM) EXTRACTS, SIMETHICONE, PARFUM, MAGNESIUM ALUMINUM SILICATE, XANTHAN GUM, TRISODIUM EDTA, DIAZOLIDINYL UREA, METHYLPARABEN, PROPYLPARABEN, SODIUM BENZOATE
I only use this hand cream before I sleep, and the effect is amazing, especially during winter, when my hands looks like snake skin (gross), and this is the only hand cream that works for me.
During summer I use it every other night and it really does get rid of the lines in my hands. Love it!